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Recombinant Human Interleukin 18, His-tagged

Cat.No. : IL18-536H
Product Overview : Recombinant human IL18 was expressed in E. coli and purified by using conventional chromatography techniques.
  • Specification
  • Gene Information
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Cat. No. : IL18-536H
Description : Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-Y)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IL-18 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration : 1 mg/ml
Source : Human
Host : E.coli
Form : Supplied as a liquid in 20mM Tris-HCl, pH 8.0, containing 10% glycerol.
Purity : > 90% by SDS - PAGE
Sequence : 36-192 amino acids: MGSSHHHHHH SSGLVPRGSH MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIY MYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYE GHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS
Molecular Mass : 20.4 kDa (178 aa), confirmed by MALDI-TOF.
Applications : SDS-PAGE
Endotoxin Levels : < 1.0 EU per ug of protein (determined by LAL method)
Storage : Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name : IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens ]
Official Symbol : IL18
Synonyms : IL18; IGIF; IL-18; IL-1g; IL1F4; MGC12320; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; IFN-gamma-inducing factor
Gene ID : 3606
mRNA Refseq : NM_001562
Protein Refseq : NP_001553
MIM : 600953
UniProt ID : Q14116
Chromosome Location : 11q22.2-q22.3
Pathway : African trypanosomiasis; Cellular roles of Anthrax toxin; Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Immune System
Function : Cytokine activity; signal transducer activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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