"IL18" Related Products

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Recombinant Human Interleukin 18, His-tagged

Cat. No.: IL18-536H
Product Overview: Recombinant human IL18 was expressed in E. coli and purified by using conventional chromatography techniques.
Description: Interleukin 18 (IL-18), previously known as interferon-gamma (IFN-Y)-inducing factor, is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IL-18 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Concentration: 1 mg/ml
Source: Human
Host: E.coli
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, containing 10% glycerol.
Purity: > 90% by SDS - PAGE
Sequence: 36-192 amino acids: MGSSHHHHHH SSGLVPRGSH MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIY MYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYE GHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS
Molecular Mass: 20.4 kDa (178 aa), confirmed by MALDI-TOF.
Applications: SDS-PAGE
Endotoxin Levels: < 1.0 EU per ug of protein (determined by LAL method)
Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens ]
Official Symbol: IL18
Synonyms: IL18; IGIF; IL-18; IL-1g; IL1F4; MGC12320; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; IFN-gamma-inducing factor
Gene ID: 3606
mRNA Refseq: NM_001562
Protein Refseq: NP_001553
MIM: 600953
UniProt ID: Q14116
Chromosome Location: 11q22.2-q22.3
Pathway: African trypanosomiasis; Cellular roles of Anthrax toxin; Cytokine Signaling in Immune system; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Immune System
Function: Cytokine activity; signal transducer activity

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