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Recombinant Human Insulin-Like Growth Factor Binding Protein 7

Cat.No. : IGFBP7-5054H
Product Overview : Recombinant human IGFBP7 was expressed in E. coli and purified by using conventional chromatography techniques.
  • Specification
  • Gene Information
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Cat. No. : IGFBP7-5054H
Description : IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF1n a manner that inhibits IGF1nduced differentiation of skeletal myoblasts, without affecting IGF1nduced proliferation.
Source : Human
Host : E.coli
Form : Supplied as a lyophilized powder.
Purity : >98% pure by SDS PAGE and HPLC
Sequence : Region of IGF BP7 protein corresponding to amino acids MSSSDTCGPC EPASCPPLPP LGCLLGETRD ACGCCPMCAR GEGEPCGGGG AGRGYCAPGM ECVKSRKRRK GKAGAAAGGP GVSGVCVCKS RYPVCGSDGT TYPSGCQLRA ASQRAESRGE KAITQVSKGT CEQGPSIVTP PKDIWNVTGA QVYLSCEVIG IPTPVLIWNK VKRGHYGVQR TE
Molecular Mass : 26.4 kDa
Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels : Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Storage : Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name : IGFBP7 insulin-like growth factor binding protein 7 [ Homo sapiens ]
Official Symbol : IGFBP7
Synonyms : insulin-like growth factor binding protein 7; PSF; FSTL2; MAC25; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP7; IBP-7; IGFBP-rP1; TAF; IGF-binding protein 7; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor
Gene ID : 3490
mRNA Refseq : NM_001553
Protein Refseq : NP_001544
MIM : 602867
UniProt ID : Q16270
Chromosome Location : 4q12
Pathway : Senescence and Autophagy
Function : insulin-like growth factor binding; protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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