"IGFBP7" Related Products

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Recombinant Human Insulin-Like Growth Factor Binding Protein 7

Cat. No. : IGFBP7-5054H
Product Overview : Recombinant human IGFBP7 was expressed in E. coli and purified by using conventional chromatography techniques.
Description : IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF1n a manner that inhibits IGF1nduced differentiation of skeletal myoblasts, without affecting IGF1nduced proliferation.
Source : Human
Host : E.coli
Form : Supplied as a lyophilized powder.
Purity : >98% pure by SDS PAGE and HPLC
Sequence : Region of IGF BP7 protein corresponding to amino acids MSSSDTCGPC EPASCPPLPP LGCLLGETRD ACGCCPMCAR GEGEPCGGGG AGRGYCAPGM ECVKSRKRRK GKAGAAAGGP GVSGVCVCKS RYPVCGSDGT TYPSGCQLRA ASQRAESRGE KAITQVSKGT CEQGPSIVTP PKDIWNVTGA QVYLSCEVIG IPTPVLIWNK VKRGHYGVQR TE
Molecular Mass : 26.4 kDa
Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels : Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Storage : Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name : IGFBP7 insulin-like growth factor binding protein 7 [ Homo sapiens ]
Official Symbol : IGFBP7
Synonyms : insulin-like growth factor binding protein 7; PSF; FSTL2; MAC25; IGFBP-7; IGFBP-7v; IGFBPRP1; IGFBP7; IBP-7; IGFBP-rP1; TAF; IGF-binding protein 7; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor
Gene ID : 3490
mRNA Refseq : NM_001553
Protein Refseq : NP_001544
MIM : 602867
UniProt ID : Q16270
Chromosome Location : 4q12
Pathway : Senescence and Autophagy
Function : insulin-like growth factor binding; protein binding

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