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Recombinant Human IFNA1 protein

Cat.No. : IFNA1-06H
Product Overview : Recombinant Human IFNA1 alpha 1a protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
  • Related Products
Description : IFN-αs are proteins secreted by leukocyte. They are mainly involved in innate immune response against viral infection. The IFN-α family has 13 subtypes and 23 different variants. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered solution in PBS, pH 7.4, containing 3 % Mannitol, 5 % Trehalose, 0.05 % Tween-80.
Bio-activity : Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 1.0 × 10⁸ IU/mg.
Molecular Mass : Approximately 19.5 kDa, a single non-glycosylated polypeptide chain containing 167 amino acids.
Protein length : 167
AA Sequence : MCDLPETHSLDNRRTLMLLAQMSRI SPSSCLMDRHDFGFPQEEFDGNQFQ KAPAISVLHELIQQIFNLFTTKDSS AAWDEDLLDKFCTELYQQLNDLEAC VMQEERVGETPLMNADSILAVKKYF RRITLYLTEKKYSPCAWEVVRAEIM RSLSLSTNLQERLRRKE
Endotoxin : Less than 0.1 EU/µg of rHuIFN-α1a as determined by LAL method.
Purity : >97% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : IFNA1
Official Symbol : IFNA1
Synonyms : IFNA1; interferon, alpha 1; interferon alpha-1/13; IFL; IFN; IFN ALPHA; IFN alpha 1b; IFN alphaD; IFNA13; IFNA@; interferon alpha 1b; leIF D; IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; interferon alpha-D; IFN-ALPHA; IFN-alphaD; MGC138207; MGC138505; MGC138507;
Gene ID : 3439
mRNA Refseq : NM_024013
Protein Refseq : NP_076918
MIM : 147660
UniProt ID : P01562

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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