Recombinant Human Prolactin
Cat.No. : | PRL-56H |
Product Overview : | Recombinant Human Prolactin produced inE.Coliis a single, non-glycosylated polypeptide chain containing 200 amino acids and having a molecular mass of 23007 Dalton. The Prolactin is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PRL-56H |
Description : | Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity : | Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | The protein was lyophilized from a concentrated (1 mg/ml) solution with 10 mM sodium Phosphate buffer pH=8 and 50 mM Nacl. |
Solubility : | It is recommended to reconstitute the lyophilized Prolactin in sterile 18 MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
Amino Acid Sequence : | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Leu-Pro-Ile-Cys. |
Biological Activity : | The ED50as determined by the dose-dependant stimulation of the proliferation of rat lymphoma, Nb2-11 was found to be < 0.065 ng/ml. |
Storage : | Lyophilized Prolactin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Prolactin should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | PRL prolactin [ Homo sapiens ] |
Synonyms : | PRL; prolactin; OTTHUMP00000017727 |
Gene ID : | 5617 |
mRNA Refseq : | NM_000948 |
Protein Refseq : | NP_000939 |
MIM : | 176760 |
UniProt ID : | P01236 |
Chromosome Location : | 6p22.2-p21.3 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction |
Function : | hormone activity; prolactin receptor binding |
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◆ Native Protein | ||
PRL-111S | Active Native Sheep Prolactin | +Inquiry |
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◆ Lysates | ||
PRL-524MCL | Recombinant Mouse PRL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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