"SFRP2" Related Products

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Recombinant Human SFRP2, His-tagged

Cat.No.: SFRP2-7655H
Product Overview: Recombinant Human Secreted FrizzledRelated Protein 2/sFRP2 is produced with our mammalian cells expression system in HEK293. The target protein is expressed with sequence (Leu25Cys295) of Human sFRP2 fused with a polyhistidine tag at the Cterminus.
Description: Secreted FrizzledRelated Protein 2 (sFRP2) belongs to the secreted frizzledrelated protein (sFRP) family. sFRP2 is highly expressed in adipose tissue, small intestine and colon. SFRP2 Contains one NTR domain and one FZ (frizzled) domain which is involved in binding with Wnt ligands.Secreted frizzledrelated proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. sFRP2 may be important for eye retinal development and for myogenesis.
Source: HEK293 Cells
Species: Human
Tag: His
Form: Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.4
AA Sequence: LFLFGQPDFS YKRSNCKPIP VNLQLCHGIE YQNMRLPNLL GHETMKEVLE QAGAWIPLVM KQCHPDTKK FLCSLFAPVC LDDLDETIQP CHSLCVQVKD RCAPVMSAFG FPWPDMLECD R FPQDNDLC IPLASSDHLL PATEEAPKVC EACKNKNDDD NDIMETLCKN DFALKIKVKE IT YINRDTK IILETKSKTI YKLNGVSERD LKKSVLWLKD SLQCTCEEMN DINAPYLVMG QKQ GGELVI TSVKRWQKGQ
Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Notes: For research use only.
Storage: Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.
Gene Name: SFRP2 secreted frizzled-related protein 2 [ Homo sapiens ]
Official Symbol: SFRP2
Synonyms: SFRP2; secreted frizzled-related protein 2; FRP 2; SARP1; SDF 5; SARP-1; sFRP-2; secreted apoptosis related protein 1; secreted apoptosis-related protein 1; FRP-2; SDF-5;
Gene ID: 6423
mRNA Refseq: NM_003013
Protein Refseq: NP_003004
MIM: 604157
UniProt ID: Q96HF1
Chromosome Location: 4q31.3
Pathway: Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem;
Function: PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; endopeptidase activator activity; fibronectin binding; integrin binding; metalloenzyme activator activity; receptor agonist activity;

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