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Recombinant Human SEMG1, His-tagged

Cat.No. : SEMG1-7760H
Product Overview : Recombinant Human Semenogelin1/SEMG1 is produced with our mammalian cells expression system in HEK293. The target protein is expressed with sequence (Gln24Thr402) of Human SEMG1 fused with a polyhistidine tag at the Cterminus.
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Description : Semenogelin1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostatespecific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alphainhibin92 and alphainhibin31 are produced; they inhibit the secretion of pituitary folliclestimulating hormone. At the same time, it breaks down the gel matrix, allowing the spermatozoa to move more freely.
Source : HEK293 Cells
Species : Human
Tag : His
Form : Lyophilized from a 0.2 μM filtered solution of 20mM HacNaAc, 150mM NaCl, pH 4.5
AA Sequence : QKGGSKGRLP SEFSQFPHGQ KGQHYSGQKG KQQTESKGSF SIQYTYHVDA NDHDQSRKSQ QYDLNALHK TTKSQRHLGG SQQLLHNKQE GRDHDKSKGH FHRVVIHHKG GKAHRGTQNP S QDQGNSPS GKGISSQYSN TEERLWVHGL SKEQTSVSGA QKGRKQGGSQ SSYVLQTEEL VA NKQQRET KNSHQNKGHY QNVVEVREEH SSKVQTSLCP AHQDKLQHGS KDIFSTQDEL LVY NKNQHQ TKNLNQDQQH
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Notes : For research use only.
Storage : Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.
Gene Name : SEMG1 semenogelin I [ Homo sapiens ]
Official Symbol : SEMG1
Synonyms : SEMG1; semenogelin I; SEMG; semenogelin-1; cancer/testis antigen 103; CT103; semen coagulating protein; SGI; dJ172H20.2; FLJ78262; MGC14719;
Gene ID : 6406
mRNA Refseq : NM_003007
Protein Refseq : NP_002998
MIM : 182140
UniProt ID : P04279
Chromosome Location : 20q12-q13.2
Pathway : Amyloids, organism-specific biosystem; Disease, organism-specific biosystem;
Function : structural molecule activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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