Native Human Serum Alpha 2 MacroGlobulin


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Native Human Serum Alpha 2 MacroGlobulin

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Cat.No. : A2M-8019H
Product Overview : Human Serum Alpha 2 MacroGlobulin was purified from Human Serum.
Description : Human Alpha-2-macroglobulin(A2M)is a large plasma protein found in the blood. Human Alpha-2-macroglobulin (A2M) is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis.Human Alpha-2-macroglobulin(A2M)levels are increased in nephrotic syndrome, a condition wherein the kidneys start to leak out some of the smaller blood proteins.
Source : Human Serum
Species : Human
Form : Lyophilized from 0.02M Tris, 0.15M NaCl
Molecular Mass : 650-800 kDa
Purity : >96% by SDS-PAGE
Stability : 1 year
Storage : 2-8 °C
Concentration : Typically >1.0 mg/mL (dispensing solution)
Gene Name : A2M alpha-2-macroglobulin [ Homo sapiens ]
Official Symbol : A2M
Synonyms : A2M; alpha-2-macroglobulin; CPAMD5; FWP007; S863 7; alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; A2MD; S863-7; DKFZp779B086;
Gene ID : 2
mRNA Refseq : NM_000014
Protein Refseq : NP_000005
MIM : 103950
UniProt ID : P01023
Chromosome Location : 12p13.31
Pathway : Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Hemostasis, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem;
Function : enzyme binding; growth factor binding; interleukin-1 binding; interleukin-8 binding; protein binding; serine-type endopeptidase inhibitor activity; tumor necrosis factor binding;

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