Recombinant Human MAGOHB, His-tagged

• Cat.No.: MAGOHB-7620H
• Product Overview: Recombinant human MAGOHB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: MAGOHB is involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway. Also, it is interacts with RBM8A and is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, UPF3B, UPF2 and ALYREF/THOC4.?
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT 30% glycerol, 0.15M NaCl
• Molecular Mass: 19.7kDa (171aa)
• Protein length: 1-148aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAVASDF YLRYYVGHKG KFGHEFLEFE FRPDGKLRYA NNSNYKNDVM IRKEAYVHKS VMEELKRIID DSEITKEDDA LWPPPDRVGR QELEIVIGDE HISFTTSKIG SLIDVNQSKD PEGLRVFYYL VQDLKCLVFS LIGLHFKIKP I
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: MAGOHB mago-nashi homolog B (Drosophila) [ Homo sapiens ]
• Official Symbol: MAGOHB
• Synonyms: MAGOHB; mago-nashi homolog B (Drosophila); protein mago nashi homolog 2; FLJ10292; MGN2; mago-nashi homolog 2; mago; magoh
• Gene ID: 55110
• mRNA Refseq: NM_018048
• Protein Refseq: NP_060518
• UniProt ID: Q96A72
• Chromosome Location: 12p13.2
• Pathway: Exon junction complex (EJC), organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem
• Function: RNA binding