Recombinant Human REXO2, His-tagged

• Cat.No.: REXO2-7641H
• Product Overview: Recombinant human REXO2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: REXO2 is a 3"-to-5" exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.?
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol
• Molecular Mass: 26.8kDa (235aa)
• Protein length: 26-237 aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSVREGGAA MAAGESMAQR MVWVDLEMTG LDIEKDQIIE MACLITDSDL NILAEGPNLI IKQPDELLDS MSDWCKEHHG KSGLTKAVKE STITLQQAEY EFLSFVRQQT PPGLCPLAGN SVHEDKKFLD KYMPQFMKHL HYRIIDVSTV KELCRRWYPE EYEFAPKKAA SHRALDDISE SIKELQFYRN NIFKKKIDEK KRKIIENGEN EKTVS
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml?

Gene Information

• Gene Name: REXO2 REX2, RNA exonuclease 2 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: REXO2
• Synonyms: REXO2; REX2, RNA exonuclease 2 homolog (S. cerevisiae); oligoribonuclease, mitochondrial; CGI 114; DKFZP566E144; SFN; small fragment nuclease; RNA exonuclease 2 homolog; RFN; REX2; CGI-114; MGC111570; DKFZp566E144
• Gene ID: 25996
• mRNA Refseq: NM_015523
• Protein Refseq: NP_056338
• MIM: 607149
• UniProt ID: Q9Y3B8
• Chromosome Location: 11q23.2
• Pathway: Ribosome biogenesis in eukaryotes, organism-specific biosystem; Ribosome biogenesis in eukaryotes, conserved biosystem
• Function: 3-5 exonuclease activity; nucleic acid binding