Active Recombinant Human GPT

• Cat.No.: GPT-33H
• Product Overview: Recombinant Human GPT was expressed in E.coli.

Specification

• Cat. No.: GPT-33H
• Description: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
• Source: E. coli
• Molecular Mass: 54,479 of subunit deduced from gene sequence
• Form: Liquid with Bufferized solution
• Purity: Single major band visualized
• Activity: Typically >1,000 u/mL
• Applications: Calibrator/Control for ALT activity assay, Standard antigen for Immunoblotting, Standard antigen for ELISA.
• Storage: -20 oC
• OfficialSymbol: GPT

Gene Information

• Gene Name: GPT glutamic-pyruvate transaminase (alanine aminotransferase) [ Homo sapiens ]
• Synonyms: GPT; glutamic-pyruvate transaminase (alanine aminotransferase); AAT1; ALT1; GPT1; Alanine aminotransferase 1; Glutamic--pyruvic transaminase 1; Glutamate pyruvate transaminase 1; EC 2.6.1.2; glutamic pyruvate transaminase
• Gene ID: 2875
• mRNA Refseq: NM_005309
• Protein Refseq: NP_005300
• MIM: 138200
• UniProt ID: P24298
• Chromosome Location: 8q24.3
• Pathway: Alanine, aspartate and glutamate metabolism; Alanine and aspartate metabolism; Metabolism; alanine biosynthesis II; Metabolism of amino acids
• Function: L-alanine:2-oxoglutarate aminotransferase activity; pyridoxal phosphate binding