Recombinant Human CXCR5
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Cat.No. : | CXCR5-9162H |
Product Overview : | Recombinant human full-length CXCR5 protein was expressed in vitro wheat germ expression system. |
Description : | This gene was identified as a gene specifically expressed in Burkitt''s lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist. |
Source : | wheat germ |
Species : | Human |
Form : | Liquid. |
Molecular Mass : | 42kDa |
AA Sequence : | MNYPLTLEMD LENLEDLFWE LDRLDNYNDT SLVENHLCPA TEGPLMASFK AVFVPVAYSL IFLLGVIGNV LVLVILERHR QTRSSTETFL FHLAVADLLL VFILPFAVAE GSVGWVLGTF LCKTVIALHK VNFYCSSLLL ACIAVDRYLA IVHAVHAYRH RRLLSIHITC GTIWLVGFLL ALPEILFAKV SQGHHNNSLP RCTFSQENQA ETHAWFTSRF LYHVAGFLLP MLVMGWCYVG VVHRLRQAQR RPQRQKAVRV AILVTSIFFL CWSPYHIVIF LDTLARLKAV DNTCKLNGSL PVAITMCEFL GLAHCCLNPM LYTFAGVKFR SDLSRLLTKL GCTGPASLCQ LFPSWRRSSL SESENATSLT TF |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | CXCR5 chemokine (C-X-C motif) receptor 5 [ Homo sapiens ] |
Official Symbol : | CXCR5 |
Synonyms : | CXCR5; chemokine (C-X-C motif) receptor 5; BLR1, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C X C motif) receptor 5) , Burkitt lymphoma receptor 1, GTP binding protein; C-X-C chemokine receptor type 5; CD185; MDR15; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); BLR1; MGC117347; |
Gene ID : | 643 |
mRNA Refseq : | NM_001716 |
Protein Refseq : | NP_001707 |
MIM : | 601613 |
UniProt ID : | P32302 |
Chromosome Location : | 11q23.3 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem; |
Function : | C-X-C chemokine receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity; |
◆ Recombinant Protein
CXCR5-9163H | Recombinant Human CXCR5, GST-tagged | +Inquiry |
CXCR5-2601C | Recombinant Chicken CXCR5 | +Inquiry |
CXCR5-1695R | Recombinant Rat CXCR5 Protein | +Inquiry |
CXCR5-4111M | Recombinant Mouse CXCR5 Protein | +Inquiry |
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◆ Lysates
CXCR5-426HCL | Recombinant Human CXCR5 cell lysate | +Inquiry |
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◆ Assay kits
Kit-1202 | cAMP CXCR5 (BLR1) CHO-K1 GPCR Assay Kit | +Inquiry |
Kit-1201 | CHO-K1 CXCR5 Bioassay Kit | +Inquiry |
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