Recombinant Rat Cd40 protein, hFc-tagged
Cat.No. : | Cd40-8726R |
Product Overview : | Recombinant Rat Cd40 protein(Q4QQW2)(Met1-Arg193), fused with hFc tag, was expressed in HEK293. |
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- Gene Information
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Source : | HEK293 |
Species : | Rat |
Tag : | hFc |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Molecular Mass : | The recombinant rat CD40/Fc is a disulfide-linked homodimer. The reduced monomer comprises 415 amino acids and has a predicted molecular mass of 46.2 kDa. The apparent molecular mass of the protein is approximately 53 kDa in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Arg193 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Cd40 CD40 molecule, TNF receptor superfamily member 5 [ Rattus norvegicus ] |
Official Symbol : | Cd40 |
Synonyms : | CD40; CD40 molecule, TNF receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40 antigen, TNF receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5; Tnfrsf5; |
Gene ID : | 171369 |
mRNA Refseq : | NM_134360 |
Protein Refseq : | NP_599187 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCD40 agonists have the potential to enhance immune responses against infectious agents, but their clinical use in this context is an area of ongoing research.
As of my knowledge cutoff date in January 2022, there were no FDA-approved drugs specifically targeting CD40. However, clinical trials were ongoing for CD40-targeted therapies.
Yes, CD40-targeted therapies are often investigated in combination with other treatments like checkpoint inhibitors or chemotherapy to enhance their effectiveness.
Side effects may include flu-like symptoms, cytokine release syndrome, and immune-related adverse events, which can be managed with supportive care and close monitoring.
Research on CD40-targeted therapies for atherosclerosis is still in the experimental stages and not yet in advanced clinical trials.
Customer Reviews (3)
Write a reviewIts utilization in this technique has allowed for precise visualization and determination of protein structures with remarkable clarity and resolution.
The reliable and high-quality results obtained using CD40 protein make it an excellent choice for researchers studying protein structures.
CD40 protein has proved to be an invaluable tool in protein electron microscopy structure analysis.
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