Recombinant Human Interferon, Beta 1, Fibroblast
Cat.No. : | IFNB1-19H |
Product Overview : | Recombinant Human Interferon-beta 1a produced inCHO (Chinese Hamster Ovarian) cellsis a single, glycosylated polypeptide chain containing 166 amino acids and having a molecular mass of 22500 Dalton. IFN-beta1a is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IFNB1-19H |
Description : | Interferon-beta 1b has antiviral, antibacterial and anticancer activities. |
Source : | CHO (Chinese Hamster Ovarian) cells |
Amino Acid Sequence : | The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Tyr-Asn-Leu-Leu. |
Physical Appearance : | Lyophilized from 1mg/ml solution containing 91 mg Human Albumin, and 620mg mannitol, and 9 mg Sodium Acetate. |
Purity : | Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | Lyophilized from a concentrated 1mg/ml solution containing PBS 7.4. |
Solubility : | It is recommended to reconstitute the lyophilized Interferon beta 1a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Biological Activity : | The specific activity as determined in a viral resistance assay (human "Wish" cell line and VSV virus or the monkey VERO cell line with EMCV virus) was found to be 270 x 10⁶ IU/mg. |
Storage : | Lyophilized Interferon-beta 1a although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution IFN-Beta1a should be stored at 4℃ between 2-7 days and for future use below -18℃.Please prevent freeze-thaw cycles. |
Gene Name : | IFNB1 interferon, beta 1, fibroblast [ Homo sapiens ] |
Synonyms : | IFNB1; Interferon, beta 1, fibroblast; IFB; IFF; IFNB; MGC96956; Interferon beta; Leukocyte interferon; B cell interferon; Type I interferon; IFNB1; IFN-b 1a; IFN-beta; OTTHUMP00000021131; Fibroblast interferon |
Gene ID : | 3456 |
mRNA Refseq : | NM_002176 |
Protein Refseq : | NP_002167 |
MIM : | 147640 |
UniProt ID : | P01574 |
Chromosome Location : | 9p21 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway |
Function : | cytokine activity; interferon-alpha/beta receptor binding; transcription corepressor activity |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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