Recombinant Human IL6, His-tagged

Cat. No.: IL6-63H
Product Overview: Recombinant Human IL-6 produced inE.Coliis single, a non-glycosylated, Polypeptide chain containing 184 amino acids fragment (29-211) and having a total molecular mass of 25.4 kDa with an amino-terminal hexahistidine tag. The IL-6-His is purified by proprietary chromatographic techniques.
Description: Interleukin-6 is a potent pro-inflammatory cytokine primarily produced by activated T cells and an assortment of other cells including endothelial cells and macrophages. IL-6 affects B and T lymphocytes and has been shown to have a role in host defense, acute phase reactions, immune responses and hematopoiesis.
Source: Escherichia Coli.
Physical Appearance: Sterile Filtered clear solution (0.25 mg/ml).
Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation: Interleukin-6 His-Tag protein is supplied in 1xPBS and 50% glycerol.
Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Gene Name: IL6 interleukin 6 (interferon, beta 2) [ Homo sapiens ]
Synonyms: IL6; interleukin 6 (interferon, beta 2); HGF; HSF; BSF2; IL-6; IFNB2;B-cell stimulatory factor 2; BSF-2; Interferon beta-2; Hybridoma growth factor; CTL differentiation factor; CDF; B cell stimulatory factor-2; B-cell differentiation factor; interleukin 6; interleukin BSF-2
Gene ID: 3569
mRNA Refseq: NM_000600
Protein Refseq: NP_000591
UniProt ID: P05231
Chromosome Location: 7p21
MIM: 147620
Pathway: Cytokine-cytokine receptor interaction; Graft-versus-host disease; Hematopoietic cell lineage; Hypertrophic cardiomyopathy (HCM); Jak-STAT signaling pathway; Pathways in cancer; Prion diseases; Toll-like receptor signaling pathway
Function: cytokine activity; growth factor activity; interleukin-6 receptor binding

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