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Recombinant Human NKIRAS2, His-tagged

Cat.No. : NKIRAS2-15859H
Product Overview : Recombinant human NKIRAS2 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Description : NFKB inhibitor interacting Ras-like 2 (NKIRAS2), also known as KBRAS2, is similar to the Ras-like small GTPases that associate with IkappaB. These Ras-like proteins, NKIRAS1 and NKIRAS2, interact with the PEST domains of IkB alpha and IkB beta and decrease their rate of degradation. NKIRAS2 shows 71% identity to KBRAS1. NKIRAS2 is an inhibitor of the transcription factor NF-kappaB.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Molecular Mass : 24.0 kDa (215aa), confirmed by MALDI-TOF
Protein length : 1-191aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSHMGKSCK VVVCGQASVG KTSILEQLLY GNHVVGSEMI ETQEDIYVGS IETDRGVREQ VRFYDTRGLR DGAELPRHCF SCTDGYVLVY STDSRESFQR VELLKKEIDK SKDKKEVTIV VLGNKCDLQE QRRVDPDVAQ HWAKSEKVKL WEVSVADRRSLLEPFVYLAS KMTQPQSKSA FPLSRKNKGS GSLDG
Purity : 90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : NKIRAS2 NFKB inhibitor interacting Ras-like 2 [ Homo sapiens ]
Official Symbol : NKIRAS2
Synonyms : NKIRAS2; NFKB inhibitor interacting Ras-like 2; NFKB inhibitor interacting Ras like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; DKFZP434N1526; kappaB Ras2; KBRAS2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; kappaB-Ras2; MGC74742; DKFZp434N1526;
Gene ID : 28511
mRNA Refseq : NM_001144927
Protein Refseq : NP_001138399
MIM : 604497
UniProt ID : Q9NYR9
Chromosome Location : 17q21.31
Pathway : TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function : GTP binding; GTPase activity; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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