"NKIRAS2" Related Products

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Recombinant Human NKIRAS2, His-tagged

Cat.No.: NKIRAS2-15859H
Product Overview: Recombinant human NKIRAS2 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: NFKB inhibitor interacting Ras-like 2 (NKIRAS2), also known as KBRAS2, is similar to the Ras-like small GTPases that associate with IkappaB. These Ras-like proteins, NKIRAS1 and NKIRAS2, interact with the PEST domains of IkB alpha and IkB beta and decrease their rate of degradation. NKIRAS2 shows 71% identity to KBRAS1. NKIRAS2 is an inhibitor of the transcription factor NF-kappaB.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Molecular Mass: 24.0 kDa (215aa), confirmed by MALDI-TOF
Protein length: 1-191aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGKSCK VVVCGQASVG KTSILEQLLY GNHVVGSEMI ETQEDIYVGS IETDRGVREQ VRFYDTRGLR DGAELPRHCF SCTDGYVLVY STDSRESFQR VELLKKEIDK SKDKKEVTIV VLGNKCDLQE QRRVDPDVAQ HWAKSEKVKL WEVSVADRRSLLEPFVYLAS KMTQPQSKSA FPLSRKNKGS GSLDG
Purity: 90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: NKIRAS2 NFKB inhibitor interacting Ras-like 2 [ Homo sapiens ]
Official Symbol: NKIRAS2
Synonyms: NKIRAS2; NFKB inhibitor interacting Ras-like 2; NFKB inhibitor interacting Ras like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; DKFZP434N1526; kappaB Ras2; KBRAS2; kappa B-Ras protein 2; I-kappa-B-interacting Ras-like protein 2; NFKB inhibitor interacting Ras-like protein 2; kappaB-Ras2; MGC74742; DKFZp434N1526;
Gene ID: 28511
mRNA Refseq: NM_001144927
Protein Refseq: NP_001138399
MIM: 604497
UniProt ID: Q9NYR9
Chromosome Location: 17q21.31
Pathway: TNF-alpha/NF-kB Signaling Pathway, organism-specific biosystem;
Function: GTP binding; GTPase activity; nucleotide binding;

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