"ACADM" Related Products

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Recombinant Human ACADM, His-tagged

Cat.No.: ACADM-9268H
Product Overview: Recombinant Human ACADM protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: 70-421a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain [ Homo sapiens ]
Official Symbol: ACADM
Synonyms: ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl Coenzyme A dehydrogenase, C 4 to C 12 straight chain; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD1; MCAD; MCADH; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain;
Gene ID: 34
mRNA Refseq: NM_000016
Protein Refseq: NP_000007
MIM: 607008
UniProt ID: P11310
Chromosome Location: 1p31
Pathway: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA, organism-specific biosystem; Beta oxidation of octanoyl-CoA to hexanoyl-CoA, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem;
Function: acryloyl-CoA reductase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; identical protein binding; medium-chain-acyl-CoA dehy

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