Recombinant Human ACADM, His-tagged
Cat.No. : | ACADM-9268H |
Product Overview : | Recombinant Human ACADM protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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- Gene Information
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Description : | This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 70-421a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain [ Homo sapiens ] |
Official Symbol : | ACADM |
Synonyms : | ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl Coenzyme A dehydrogenase, C 4 to C 12 straight chain; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD1; MCAD; MCADH; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; |
Gene ID : | 34 |
mRNA Refseq : | NM_000016 |
Protein Refseq : | NP_000007 |
MIM : | 607008 |
UniProt ID : | P11310 |
Chromosome Location : | 1p31 |
Pathway : | Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA, organism-specific biosystem; Beta oxidation of octanoyl-CoA to hexanoyl-CoA, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; |
Function : | acryloyl-CoA reductase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; flavin adenine dinucleotide binding; identical protein binding; medium-chain-acyl-CoA dehy |
Products Types
◆ Recombinant Protein | ||
ACADM-23H | Recombinant Human ACADM Protein, His-tagged | +Inquiry |
ACADM-238M | Recombinant Mouse ACADM Protein, His (Fc)-Avi-tagged | +Inquiry |
Acadm-503M | Recombinant Mouse Acadm Protein, MYC/DDK-tagged | +Inquiry |
ACADM-0657H | Recombinant Human ACADM Protein (Lys26-Asn421), N-His-tagged | +Inquiry |
ACADM-134H | Recombinant Human ACADM Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
ACADM-9114HCL | Recombinant Human ACADM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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