"ALDOA" Related Products

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Recombinant Human ALDOA, His-tagged

Cat.No.: ALDOA-9566H
Product Overview: Recombinant Human ALDOA protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-363a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: ALDOA aldolase A, fructose-bisphosphate [ Homo sapiens ]
Official Symbol: ALDOA
Synonyms: ALDOA; aldolase A, fructose-bisphosphate; fructose-bisphosphate aldolase A; muscle-type aldolase; lung cancer antigen NY-LU-1; fructose-1,6-bisphosphate triosephosphate-lyase; ALDA; GSD12;
Gene ID: 226
mRNA Refseq: NM_000034
Protein Refseq: NP_000025
MIM: 103850
UniProt ID: P04075
Chromosome Location: 16p11.2
Pathway: Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem;
Function: actin binding; cytoskeletal protein binding; fructose binding; fructose-bisphosphate aldolase activity; identical protein binding; lyase activity; tubulin binding;

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