Recombinant Human ATP6V1E1, GST-tagged
Cat.No. : | ATP6V1E1-10046H |
Product Overview : | Recombinant Human ATP6V1E1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-226a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 [ Homo sapiens ] |
Official Symbol : | ATP6V1E1 |
Synonyms : | ATP6V1E1; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1; ATP6E, ATP6V1E, ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD , ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E isoform 1; V-type proton ATPase subunit E 1; ATP6E2; P31; Vma4; V-ATPase, subunit E; V-ATPase subunit E 1; V-ATPase 31 kDa subunit; vacuolar proton pump subunit E 1; H+-transporting ATP synthase chain E, vacuolar; H(+)-transporting two-sector ATPase, 31kDa subunit; ATP6E; ATP6V1E; |
Gene ID : | 529 |
mRNA Refseq : | NM_001039366 |
Protein Refseq : | NP_001034455 |
MIM : | 108746 |
UniProt ID : | P36543 |
Chromosome Location : | 22q11.2 |
Pathway : | Collecting duct acid secretion, organism-specific biosystem; Collecting duct acid secretion, conserved biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Insulin receptor recycling, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | hydrogen-exporting ATPase activity, phosphorylative mechanism; hydrolase activity; protein binding; proton-transporting ATPase activity, rotational mechanism; |
Products Types
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ATP6V1E1-549R | Recombinant Rat ATP6V1E1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP6V1E1-386H | Recombinant Human ATP6V1E1, T7-tagged | +Inquiry |
◆ Lysates | ||
ATP6V1E1-8580HCL | Recombinant Human ATP6V1E1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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