"B3GALT2" Related Products

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Recombinant Human B3GALT2, His-tagged

Cat.No.: B3GALT2-10096H
Product Overview: Recombinant Human B3GALT2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose.
Source: E.coli
Species: Human
Tag: His
Protein length: 47-422a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 [ Homo sapiens ]
Official Symbol: B3GALT2
Synonyms: B3GALT2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2; beta-1,3-galactosyltransferase 2; beta3Gal T2; beta-3-galt2; beta-1,3-GalTase 2; UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2; GLCT2; BETA3GALT2; beta3Gal-T2;
Gene ID: 8707
mRNA Refseq: NM_003783
Protein Refseq: NP_003774
MIM: 603018
UniProt ID: O43825
Chromosome Location: 1q31
Pathway: Glycosphingolipid biosynthesis - lacto and neolacto series, organism-specific biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, conserved biosystem; Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer, organism-specific biosystem; Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer, conserved biosystem; Metabolic pathways, organism-specific biosystem;
Function: UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity; galactosyltransferase activity; transferase activity, transferring glycosyl groups;

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