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Recombinant Human BCL2L10, His-tagged

Cat.No. : BCL2L10-10179H
Product Overview : Recombinant Human BCL2L10 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-172a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : BCL2L10 BCL2-like 10 (apoptosis facilitator) [ Homo sapiens ]
Official Symbol : BCL2L10
Synonyms : BCL2L10; BCL2-like 10 (apoptosis facilitator); bcl-2-like protein 10; BCL B; Boo; Diva; bcl2-L-10; apoptosis regulator Bcl-B; anti-apoptotic protein NrH; BCL-B; MGC129810; MGC129811;
Gene ID : 10017
mRNA Refseq : NM_020396
Protein Refseq : NP_065129
MIM : 606910
UniProt ID : Q9HD36
Chromosome Location : 15q21
Function : protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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