Recombinant Human CBR3, GST-tagged

• Cat.No.: CBR3-10763H
• Product Overview: Recombinant Human CBR3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-277a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CBR3 carbonyl reductase 3 [ Homo sapiens ]
• Official Symbol: CBR3
• Synonyms: CBR3; carbonyl reductase 3; carbonyl reductase [NADPH] 3; SDR21C2; short chain dehydrogenase/reductase family 21C; member 2; carbonyl reductase (NADPH) 3; NADPH-dependent carbonyl reductase 3; short chain dehydrogenase/reductase family 21C, member 2; hCBR3
• Gene ID: 874
• mRNA Refseq: NM_001236
• Protein Refseq: NP_001227
• MIM: 603608
• UniProt ID: O75828
• Chromosome Location: 21q22.2
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, organism-specific biosystem; Metabolism of xenobiotics by cytochrome P450, conserved biosystem
• Function: 3-keto sterol reductase activity; NADPH binding; carbonyl reductase (NADPH) activity; nucleotide binding; oxidoreductase activity