Recombinant Human DDX46, GST-tagged

• Cat.No.: DDX46-11906H
• Product Overview: Recombinant Human DDX46 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 682-1031a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [ Homo sapiens ]
• Official Symbol: DDX46
• Synonyms: DDX46; DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; probable ATP-dependent RNA helicase DDX46; FLJ25329; KIAA0801; Prp5; PRPF5; PRP5 homolog; RNA helicase; DEAD box protein 46; Prp5-like DEAD-box protein; MGC9936
• Gene ID: 9879
• mRNA Refseq: NM_014829
• Protein Refseq: NP_055644
• UniProt ID: Q7L014
• Chromosome Location: 5q31.1
• Pathway: Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem
• Function: ATP binding; ATP-dependent helicase activity; RNA binding; helicase activity; hydrolase activity; nucleotide binding