"EIF3D" Related Products

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Recombinant Human EIF3D, His-tagged

Cat.No.: EIF3D-12366H
Product Overview: Recombinant Human EIF3D protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex.
Source: E.coli
Species: Human
Tag: His
Protein length: 323-531a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: EIF3D eukaryotic translation initiation factor 3, subunit D [ Homo sapiens ]
Official Symbol: EIF3D
Synonyms: EIF3D; eukaryotic translation initiation factor 3, subunit D; EIF3S7, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; eukaryotic translation initiation factor 3 subunit D; eIF3 p66; eIF3 zeta; eIF3d; eIF-3-zeta; translation initiation factor eIF3 p66 subunit; eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; EIF3S7; eIF3-p66; eIF3-zeta; MGC17258; MGC126526;
Gene ID: 8664
mRNA Refseq: NM_003753
Protein Refseq: NP_003744
MIM: 603915
UniProt ID: O15371
Chromosome Location: 22q13.1
Pathway: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of a pool of free 40S subunits, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem; Gene Expression, organism-specific biosystem;
Function: protein binding; contributes_to translation initiation factor activity; contributes_to translation initiation factor activity;

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