Recombinant Human EXOSC5, His-tagged

• Cat.No.: EXOSC5-12598H
• Product Overview: Recombinant Human EXOSC5 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-235a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: EXOSC5 exosome component 5 [ Homo sapiens ]
• Official Symbol: EXOSC5
• Synonyms: EXOSC5; exosome component 5; exosome complex component RRP46; exosome component Rrp46; hRrp46p; MGC12901; p12B; RRP41B; RRP46; Rrp46p; exosome complex exonuclease RRP46; ribosomal RNA-processing protein 46; chronic myelogenous leukemia tumor antigen 28; MGC111224
• Gene ID: 56915
• mRNA Refseq: NM_020158
• Protein Refseq: NP_064543
• MIM: 606492
• UniProt ID: Q9NQT4
• Chromosome Location: 19q13.1
• Pathway: Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem
• Function: 3-5-exoribonuclease activity; RNA binding; NOT exoribonuclease activity; protein binding