Recombinant Human FUSIP1, GST-tagged
| Cat.No. : | FUSIP1-13038H |
| Product Overview : | Recombinant Human FUSIP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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| Description : | This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist. |
| Source : | E.coli |
| Species : | Human |
| Tag : | GST |
| Protein length : | 8-183a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
| Gene Name : | SRSF10 serine/arginine-rich splicing factor 10 [ Homo sapiens ] |
| Official Symbol : | SRSF10 |
| Synonyms : | SRSF10; serine/arginine-rich splicing factor 10; FUS interacting protein (serine/arginine rich) 1 , FUS interacting protein (serine arginine rich) 2 , FUSIP1, FUSIP2, neural salient SR protein , SFRS13A, splicing factor, arginine/serine rich 13A; NSSR; SFRS13; splicing factor; arginine/serine rich 13; SR splicing factor 10; SRp38; SRrp40; TASR1; TASR2; splicing factor SRp38; TLS-associated SR protein; neural-salient SR protein; 40 kDa SR-repressor protein; TLS-associated protein TASR; TLS-associated protein with SR repeats; TLS-associated serine-arginine protein 1; TLS-associated serine-arginine protein 2; splicing factor, arginine/serine-rich 13; splicing factor, arginine/serine-rich 13A; serine-arginine repressor protein (40 kDa); TLS-associated protein with Ser-Arg repeats; FUS-interacting serine-arginine-rich protein 1; FUS interacting protein (serine-arginine rich) 1; FUS-interacting protein (serine-arginine rich) 2; TASR; FUSIP1; FUSIP2; SFRS13A; FLJ30749; FLJ43846; DKFZp686H0644; |
| Gene ID : | 10772 |
| mRNA Refseq : | NM_001191005 |
| Protein Refseq : | NP_001177934 |
| MIM : | 605221 |
| UniProt ID : | O75494 |
| Chromosome Location : | 1p36.11 |
| Pathway : | Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA processing, organism-specific biosystem; |
| Function : | RNA binding; RS domain binding; nucleic acid binding; nucleotide binding; protein binding; unfolded protein binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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