Recombinant Human FXYD1, GST-tagged
Cat.No. : | FXYD1-13054H |
Product Overview : | Recombinant Human FXYD1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5 UTR sequences have been described in the literature. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-92a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | FXYD1 FXYD domain containing ion transport regulator 1 [ Homo sapiens ] |
Official Symbol : | FXYD1 |
Synonyms : | FXYD1; FXYD domain containing ion transport regulator 1; phospholemman , PLM; phospholemman; PLM; MGC44983; |
Gene ID : | 5348 |
mRNA Refseq : | NM_005031 |
Protein Refseq : | NP_005022 |
MIM : | 602359 |
UniProt ID : | O00168 |
Chromosome Location : | 19q13.1 |
Function : | chloride channel activity; ion channel activity; |
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◆ Recombinant Protein | ||
Fxyd1-3113M | Recombinant Mouse Fxyd1 Protein, Myc/DDK-tagged | +Inquiry |
FXYD1-2076R | Recombinant Rat FXYD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FXYD1-3400M | Recombinant Mouse FXYD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FXYD1-2420R | Recombinant Rat FXYD1 Protein | +Inquiry |
FXYD1-6103M | Recombinant Mouse FXYD1 Protein | +Inquiry |
◆ Lysates | ||
FXYD1-6104HCL | Recombinant Human FXYD1 293 Cell Lysate | +Inquiry |
FXYD1-6105HCL | Recombinant Human FXYD1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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