"FXYD4" Related Products

Recombinant Human FXYD4, GST-tagged

Cat.No.: FXYD4-13057H
Product Overview: Recombinant Human FXYD4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na,K-ATPase, as has FXYD2, also known as the gamma subunit of the Na,K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-89a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: FXYD4 FXYD domain containing ion transport regulator 4 [ Homo sapiens ]
Official Symbol: FXYD4
Synonyms: FXYD domain containing ion transport regulator 4; 4028; Ensembl:ENSG00000150201; FXYD domain-containing ion transport regulator 4;channel-inducing factor; CHIF
Gene ID: 53828
mRNA Refseq: NM_001184963.1
Protein Refseq: NP_001171892.1
UniProt ID: P59646
Chromosome Location: 10q11.21
Pathway: Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem;
Function: ATPase binding; potassium channel activity;

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