Recombinant Human GLUD1, His-tagged

• Cat.No.: GLUD1-13319H
• Product Overview: Recombinant Human GLUD1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 214-558a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GLUD1 glutamate dehydrogenase 1 [ Homo sapiens ]
• Official Symbol: GLUD1
• Synonyms: GLUD1; glutamate dehydrogenase 1; GLUD; glutamate dehydrogenase 1, mitochondrial; GDH; GDH 1; glutamate dehydrogenase (NAD(P)+); GDH1; MGC132003
• Gene ID: 2746
• mRNA Refseq: NM_005271
• Protein Refseq: NP_005262
• MIM: 138130
• UniProt ID: P00367
• Chromosome Location: 10q23.2
• Pathway: Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; D-Glutamine and D-glutamate metabolism, organism-specific biosystem; D-Glutamine and D-glutamate metabolism, conserved biosystem
• Function: ADP binding; ATP binding; GTP binding; NAD+ binding; glutamate dehydrogenase (NAD+) activity; glutamate dehydrogenase [NAD(P)+] activity; glutamate dehydrogenase [NAD(P)+] activity; identical protein binding; leucine binding; nucleotide binding; oxidoredu