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Recombinant Human HERC4, GST-tagged

Cat.No. : HERC4-13739H
Product Overview : Recombinant Human HERC4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Source : E.coli
Species : Human
Tag : GST
Protein length : 723-1049a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 [ Homo sapiens ]
Official Symbol : HERC4
Synonyms : HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4; hect domain and RLD 4; probable E3 ubiquitin-protein ligase HERC4; DKFZP564G092; KIAA1593; HECT domain and RCC1-like domain-containing protein 4; DKFZp564G092;
Gene ID : 26091
mRNA Refseq : NM_015601
Protein Refseq : NP_056416
MIM : 609248
UniProt ID : Q5GLZ8
Chromosome Location : 10
Pathway : Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem;
Function : acid-amino acid ligase activity; ligase activity; ubiquitin-protein ligase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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