Recombinant Human IL1A, GST-tagged
Cat.No. : | IL1A-14166H |
Product Overview : | Recombinant Human IL1A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimers disease. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-271a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | IL1A interleukin 1, alpha [ Homo sapiens ] |
Official Symbol : | IL1A |
Synonyms : | IL1A; interleukin 1, alpha; IL1; interleukin-1 alpha; hematopoietin 1; IL 1A; IL1 ALPHA; IL1F1; preinterleukin 1 alpha; pro interleukin 1 alpha; IL-1 alpha; hematopoietin-1; pro-interleukin-1-alpha; IL-1A; IL1-ALPHA; |
Gene ID : | 3552 |
mRNA Refseq : | NM_000575 |
Protein Refseq : | NP_000566 |
MIM : | 147760 |
UniProt ID : | P01583 |
Chromosome Location : | 2q14 |
Pathway : | Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response, organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; |
Function : | copper ion binding; cytokine activity; interleukin-1 receptor binding; protein binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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