Recombinant Human NDUFV3, His-tagged

• Cat.No.: NDUFV3-2345H
• Product Overview: Recombinant human NDUFV3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: NDUFV3 is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT, 2mM EDTA
• Molecular Mass: 10.8kDa
• Protein length: 97aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSAESGKS EKGQPQNSKK QSPPKKPAPV PAEPFDNTTY KNLQHHDYST YTFLDLNLEL SKFRMPQPSSGRESPRH
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa [ Homo sapiens ]
• Official Symbol: NDUFV3
• Synonyms: NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa; NADH dehydrogenase (ubiquinone) flavoprotein 3 (10kD); NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; CI 10k; complex I 10kDa subunit; complex I-9kD; renal carcinoma antigen NY-REN-4; NADH-ubiquinone oxidoreductase 9 kD subunit; NADH-ubiquinone oxidoreductase 9 kDa subunit; mitochondrial NADH oxidoreductase-like protein; NADH-ubiquinone oxidoreductase flavoprotein 3, 10kD; complex I, mitochondrial respiratory chain, 10-kD subunit; CI-10k; CI-9KD
• Gene ID: 4731
• mRNA Refseq: NM_001001503
• Protein Refseq: NP_001001503
• MIM: 602184
• UniProt ID: P56181
• Chromosome Location: 21q22.3
• Pathway: Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Electron Transport Chain, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: NADH dehydrogenase (ubiquinone) activity