Recombinant human RBM17, His-tagged
Cat.No. : | RBM17-2451H |
Product Overview : | Recombinant human RBM17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | RNA binding motif protein 17, also known as RBM17, is splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. This protein is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. This protein promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 47.1kDa (421aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MSLYDDLGVE TSDSKTEGWS KNFKLLQSQL QVKKAALTQA KSQRTKQSTV LAPVIDLKRG GSSDDRQIVD TPPHVAAGLK DPVPSGFSAG EVLIPLADEY DPMFPNDYEK VVKRQREERQ RQRELERQKE IEEREKRRKD RHEASGFARR PDPDSDEDED YERERRKRSM GGAAIAPPTS LVEKDKELPR DFPYEEDSRP RSQSSKAAIP PPVYEEQDRP RSPTGPSNSF LANMGGTVAH KIMQKYGFRE GQGLGKHEQG LSTALSVEKT SKRGGKIIVG DATEKDASKK SDSNPLTEIL KCPTKVVLLR NMVGAGEVDE DLEVETKEEC EKYGKVGKCV IFEIPGAPDD EAVRIFLEFE RVESAIKAVV DLNGRYFGGR VVKACFYNLD KFRVLDLAEQ V |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | RBM17 RNA binding motif protein 17 [ Homo sapiens ] |
Official Symbol : | RBM17 |
Synonyms : | RBM17; RNA binding motif protein 17; splicing factor 45; MGC14439; SPF45; splicing factor 45kDa; 45 kDa-splicing factor; RNA-binding motif protein 17; DKFZp686F13131; |
Gene ID : | 84991 |
mRNA Refseq : | NM_001145547 |
Protein Refseq : | NP_001139019 |
MIM : | 606935 |
UniProt ID : | Q96I25 |
Chromosome Location : | 10p15.1 |
Pathway : | Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA processing, organism-specific biosystem; |
Function : | RNA binding; nucleic acid binding; nucleotide binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
RBM17-7471M | Recombinant Mouse RBM17 Protein, His (Fc)-Avi-tagged | +Inquiry |
RBM17-3629R | Recombinant Rhesus Macaque RBM17 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rbm17-5410M | Recombinant Mouse Rbm17 Protein, Myc/DDK-tagged | +Inquiry |
RBM17-3812R | Recombinant Rhesus monkey RBM17 Protein, His-tagged | +Inquiry |
RBM17-11156Z | Recombinant Zebrafish RBM17 | +Inquiry |
◆ Lysates | ||
RBM17-2479HCL | Recombinant Human RBM17 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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