Active Recombinant Canine TNFRSF9 protein, His-tagged
Cat.No. : | TNFRSF9-257C |
Product Overview : | Recombinant Canine TNFRSF9 protein(XP_850336.1)(Met1-Ser185), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Canine |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its binding ability in a functional ELISA.Immobilized canine TNFRSF9-His at 10 μg/ml (100 μl/well) can bind rat Fc-TNFSF9, The EC50 of rat Fc-TNFSF9 is 0.26-0.62 μg/ml. |
Molecular Mass : | The recombinant canine TNFRSF9 comprises 173 amino acids and has a predicted molecular mass of 18.4 kDa. The apparent molecular mass of the protein is approximately 28-34 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Protein Length : | Met1-Ser185 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Products Types
◆ Recombinant Protein | ||
TNFRSF9-315H | Recombinant Human TNFRSF9 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
TNFRSF9-329H | Recombinant Human TNFRSF9 Protein (Met1-Gln186), His-tagged, Biotinylated | +Inquiry |
TNFRSF9-1233C | Acitve Recombinant Cynomolgus/Rhesus TNFRSF9 protein(Met1-Gln186), His-tagged | +Inquiry |
TNFRSF9-580H | Recombinant Human TNFRSF9 Protein | +Inquiry |
TNFRSF9-582M | Recombinant Mouse TNFRSF9 Protein | +Inquiry |
◆ Lysates | ||
TNFRSF9-928CCL | Recombinant Canine TNFRSF9 cell lysate | +Inquiry |
TNFRSF9-2162HCL | Recombinant Human TNFRSF9 cell lysate | +Inquiry |
TNFRSF9-1792MCL | Recombinant Mouse TNFRSF9 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionStudies have found that abnormal expression levels of TNFRSF9 may be associated with certain tumors, autoimmune diseases, and inflammatory diseases.
It has a variety of associations with other proteins and cytokines. For example, it may interact with the NF-kB signaling pathway to regulate the inflammatory response, and it may also interact with apoptosis-related proteins to regulate the apoptosis process.
TNFRSF9 mainly plays an important role in the immune system, as an activating signaling molecule, it is able to stimulate the activation, proliferation and survival of T cells and NK cells.
Inhibitors or activators targeting TNFRSF9 may have potential applications for the treatment of certain tumors, autoimmune diseases, and inflammatory diseases.
The extracellular domain of TNFRSF9 can bind to its ligand, such as 4-1BBL, to initiate signal transduction, which in turn activates downstream signaling pathways.
TNFRSF9 has some potential in tumor immunotherapy. Several antibody drugs have been developed to use the stimulating effects of TNFRSF9 to enhance the activity of immune cells to fight tumors.
Customer Reviews (3)
Write a reviewGood heat resistance, long time treatment at high temperature, still has activity.
The results obtained by SDS-PAGE or Western blot analysis were good.
The purity is good, and the experimental results obtained are accurate.
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