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Recombinant Human RHEB, His tagged

Cat.No. : RHEB-521H
Product Overview : Recombinant Human RHEB (Q15382) (Met1-Cys181), fused with a polyhistide tag at the N-terminus, was produced in Baculovirus-Insect cells.
  • Specification
  • Gene Information
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Source : Baculovirus-Insect cells
Species : Human
Tag : His
Predicted N Terminal : His
Form : Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% gly, pH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Molecular Mass : The recombinant human RHEB consists of 199 amino acids and has a calculated molecular mass of 22.4 kDa. The recombinant protein migrates as an approximately 21 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >85 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : RHEB Ras homolog enriched in brain [ Homo sapiens ]
Official Symbol : RHEB
Gene ID : 6009
mRNA Refseq : NM_005614
Protein Refseq : NP_005605
MIM : 601293
UniProt ID : Q15382
Chromosome Location : 7q36

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does RHEB interact with the mTOR pathway, and what implications does this have for clinical interventions 05/29/2021

RHEB directly interacts with the mTOR pathway, a key regulator of cell growth. Understanding this interaction provides insights for developing drugs that target this pathway in diseases like cancer.

Are there any experimental drugs targeting RHEB currently in development? 01/15/2020

Some experimental drugs targeting RHEB are in preclinical development, showing promise in modulating cell growth and survival.

In what ways can the clinical application of RHEB be explored in cancer treatment? 04/24/2018

RHEB's involvement in cell growth makes it a potential target for cancer therapy. Understanding its role may lead to the development of targeted therapies.

Are there any ongoing clinical trials involving RHEB protein in cancer research? 02/18/2018

Research is underway to evaluate the therapeutic potential of targeting RHEB in cancer treatment, with several clinical trials exploring its role as a therapeutic target.

How does the dysregulation of RHEB contribute to diseases? 04/23/2017

Dysregulation of RHEB is associated with various diseases, including cancer and neurological disorders, due to its impact on cell growth and survival pathways.

Customer Reviews (3)

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03/07/2020

    Researchers using RHEB protein can benefit from its high purity and quality, ensuring reliable results.

    05/24/2018

      the RHEB protein is available in different formats, including recombinant and purified variants.

      11/13/2017

        This flexibility allows researchers to select the most suitable form for their particular experimental setup, enhancing the efficiency and accuracy of their trials.

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