Recombinant Human COL21A1, His-tagged

• Cat.No.: COL21A1-72H
• Product Overview: Recombinant Human Collagen α-1(XXI) Chain/COL21A1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Tyr957) of Human COL21A1 fused with a polyhistidine tag at the C-terminus.

Specification

• Description: Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I collagen; it may serve to maintain the integrity of the extracellular matrix.
• Source: HEK293
• Species: Human
• Tag: His
• AA Sequence: EDGEVRSSCRTAPTDLVFILDGSYS VGPENFEIVKKWLVNITKNFDIGPK FIQVGVVQYSDYPVL EIPLGSYDSGEHLTAAVESILYLGG NTKTGKAIQFALDYLFAKSSRFLTK IAVVLTDGKSQDDVK DAAQAARDSKITLFAIGVGSETEDA ELRAIANKPSSTYVFYVEDYIAISK IREVMKQKLCEESVC PTRIPVAARDERGFDILLGLDVNKK VKKRIQLSPKKIKGYEVTSKVDLSE LTSNVFPEGLPPSYV FVSTQRFKVKKIWDLWRILTIDGRP QIAVTLNGVDKILLFTTTSVINGSQ VVTFANPQVKTLFDE GWHQIRLLVTEQDVTLYIDDQQIEN KPLHPVLGILINGQTQIGKYSGKEE TVQFDVQKLRIYCDP EQNNRETACEIPGFNGECLNGPSDV GSTPAPCICPPGKPGLQGPKGDPGL PGNPGYPGQPGQDGK PGYQGIAGTPGVPGSPGIQGARGLP GYKGEPGRDGDKGDRGLPGFPGLHG MPGSKGEMGAKGDKG SPGFYGKKGAKGEKGNAGFPGLPGP AGEPGRHGKDGLMGSPGFKGEAGSP GAPGQDGTRGEPGIP GFPGNRGLMGQKGEIGPPGQQGKKG APGMPGLMGSNGSPGQPGTPGSKGS KGEPGIQGMPGASGL KGEPGATGSPGEPGYMGLPGIQGKK GDKGNQGEKGIQGQKGENGRQGIPG QQGIQGHHGAKGERG EKGEPGVRGAIGSKGESGVDGLMGP AGPKGQPGDPGPQGPPGLDGKPGRE FSEQFIRQVCTDVIR AQLPVLLQSGRIRNCDHCLSQHGSP GIPGPPGPIGPEGPRGLPGLPGRDG VPGLVGVPGRPGVRG LKGLPGRNGEKGSQGFGYPGEQGPP GPPGPEGPPGISKEGPPGDPGLPGK DGDHGKPGIQGQPGP PGICDPSLCFSVIARRDPFRKGPNY VDHHHHHH
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Purity: Greater than 95% as determined by reducing SDS-PAGE.

Gene Information

• Gene Name: COL21A1 collagen, type XXI, alpha 1 [ Homo sapiens ]
• Official Symbol: COL21A1
• Synonyms: COL21A1; collagen, type XXI, alpha 1; collagen alpha-1(XXI) chain; alpha 1 type XXI collagen; alpha 1 chain-like collagen; FP633; COLA1L; dJ708F5.1; dJ682J15.1; FLJ39125; FLJ44623; MGC26619; DKFZp564B052
• Gene ID: 81578
• mRNA Refseq: NM_030820
• Protein Refseq: NP_110447
• MIM: 610002
• UniProt ID: Q96P44
• Chromosome Location: 6p12.3-p11.2
• Function: structural molecule activity