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Recombinant Human NLGN4X, His-tagged

Cat.No. : NLGN4X-158H
Product Overview : Recombinant Human Neuroligin 4, X-Linked/NLGN4X is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln42-Ser676) of Human NLGN4X fused with a polyhistidine tag at the C-terminus.
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Description : Neuroligin 4, X-Linked (NLGN4X) is a single-pass type I membrane protein that belongs to the type-B carboxylesterase/lipase family. NLGN4X is detected at higher levels in heart and at lower levels in the liver, skeletal muscle, and pancreas. NLGN4X is a putative neuronal cell surface protein involved in cell-cell-interactions. NLGN4X may act as splice site-specific ligands for β-neurexins. It has been shown that NLGN4X is involved in the formation and remodeling of central nervous system synapses. NLGN4X also interacts with discs, large (Drosophila) homolog 4 (DLG4). Defects in NLGN4X have been associated with autism and Asperger syndrome.
Source : HEK293
Species : Human
Tag : His
AA Sequence : QAQYPVVNTNYGKIRGLRTPLPNEI LGPVEQYLGVPYASPPTGERRFQPP EPPSSWTGIRNTTQF AAVCPQHLDERSLLHDMLPIWFTAN LDTLMTYVQDQNEDCLYLNIYVPTE DDIHDQNSKKPVMVY IHGGSYMEGTGNMIDGSILASYGNV IVITINYRLGILGFLSTGDQAAKGN YGLLDQIQALRWIEE NVGAFGGDPKRVTIFGSGAGASCVS LLTLSHYSEGLFQKAIIQSGTALSS WAVNYQPAKYTRILA DKVGCNMLDTTDMVECLRNKNYKEL IQQTITPATYHIAFGPVIDGDVIPD DPQILMEQGEFLNYD IMLGVNQGEGLKFVDGIVDNEDGVT PNDFDFSVSNFVDNLYGYPEGKDTL RETIKFMYTDWADKE NPETRRKTLVALFTDHQWVAPAVAT ADLHAQYGSPTYFYAFYHHCQSEMK PSWADSAHGDEVPYV FGIPMIGPTELFSCNFSKNDVMLSA VVMTYWTNFAKTGDPNQPVPQDTKF IHTKPNRFEEVAWSK YNPKDQLYLHIGLKPRVRDHYRATK VAFWLELVPHLHNLNEIFQYVSTTT KVPPPDMTSFPYGTR RSPAKIWPTTKRPAITPANNPKHSK DPHKTGPEDTTVLIETKRDYSTELS VDHHHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Gene Name : NLGN4X neuroligin 4, X-linked [ Homo sapiens ]
Official Symbol : NLGN4X
Synonyms : NLGN4X; neuroligin 4, X-linked; neuroligin 4 , NLGN4; neuroligin-4, X-linked; HLNX; KIAA1260; NLGN; neuroligin X; HNLX; HNL4X; NLGN4; ASPGX2; AUTSX2; MGC22376;
Gene ID : 57502
mRNA Refseq : NM_020742
Protein Refseq : NP_065793
MIM : 300427
UniProt ID : Q8N0W4
Chromosome Location : Xp22.33
Pathway : Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem;
Function : NOT carboxylesterase activity; chloride ion binding; neurexin family protein binding; neurexin family protein binding; protein binding; protein homodimerization activity; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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