"SIKE1" Related Products

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Recombinant Human SIKE1, His-tagged

Cat.No.: SIKE1-5122H
Product Overview: Recombinant human SIKE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: SIKE interacts with IKK-epsilon and TBK1 and acts as a suppressor of TLR3 and virus-triggered interferon activation pathways.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Molecular Mass: 26.1 kDa (230aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSCTIEK ILTDAKTLLE RLREHDAAAE SLVDQSAALH RRVAAMREAG TALPDQYQED ASDMKDMSKY KPHILLSQEN TQIRDLQQEN RELWISLEEH QDALELIMSK YRKQMLQLMV AKKAVDAEPV LKAHQSHSAE IESQIDRICE MGEVMRKAVQ VDDDQFCKIQ EKLAQLELEN KELRELLSIS SESLQARKEN SMDTASQAIK
Purity: >85% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: SIKE1 suppressor of IKBKE 1 [ Homo sapiens (human) ]
Official Symbol: SIKE1
Synonyms: SIKE1;SIKE; RP5-1000E10.4;suppressor of IKBKE 1;suppressor of IKK epsilon;suppressor of IKK-epsilon
Gene ID: 80143
mRNA Refseq: NM_001102396.1
Protein Refseq: NP_001095866.1
MIM: 611656
UniProt ID: Q9BRV8
Chromosome Location: 1p13.2
Pathway: Immune System;Innate Immune System;RIG-I-like receptor signaling pathway;RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways;TRAF3-dependent IRF activation pathway;TRAF6 mediated IRF7 activation
Function: protein binding

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