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Recombinant Rhesus monkey IL16

Cat.No.: IL16-543R
Product Overview: Recombinant Rhesus monkey IL16 produced in E. coli is approximately 12.5 kDa, a single non-glycosylated polypeptide chain containing 121 amino acids.
Description: Interleukin-16 (IL-16) is also called lymphocyte chemoattractant factor (LCF) and it is mostly secreted by lymphocytes, epithelial cells, eosinophils, and CD8+ T cells. It has many functions including induction of the IL-2Rα on T cells, suppression of human immunodeficiency virus (HIV) replication, inhibition of T-cell antigen receptor/CD3 mediated T-cell stimulation in mixed lymphocyte reactions and so on. It signals through CD4 receptor. Furthermore, recombinant rhesus macaque interleukin-16 contains 121 amino acid residues and it shares 85 % ~ 95 % a.a. sequence identity with human and murine IL-16.
Source: E. coli
Species: Rhesus monkey
Form: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Bio-activity: Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CD4+ T lymphocytes is in a concentration range of 1.0-100 ng/ml.
Molecular Mass: 12.5 kDa
AA Sequence: SAASASAASD VSVESSAEAT VYTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETIQPG DEILQLAGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QPKETTAAAD S
Endotoxin: Less than 1 EU/μg of rRhIL-16 as determined by LAL method.
Purity: >98% by SDS-PAGE and HPLC analyses.
Usage: This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Storage: This lyophilized preparation is stable at 2-8 centigrade, but should be kept at -20 centigrade for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 centigrade. For maximal stability, apport
Reconstitution: We recommend that this vial be briefy centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportion
Gene Name: IL16 interleukin 16 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol: IL16
Synonyms: IL16;IL-16;pro-interleukin-16;IL-16;interleukin 16 (lymphocyte chemoattractant factor)
Gene ID: 574100
mRNA Refseq: NM_001032808.1
Protein Refseq: NP_001027980.1
UniProt ID: O62675
Chromosome Location: chromosome: 7

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