Active Recombinant Human DNMT3L, GST-tagged

• Cat.No.: DNMT3L-166H
• Product Overview: Recombinant full-length human DNMT3L was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: Recombinant full-length human DNMT3L was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: The specific activity of DNMT3A (0.25μg) was increased 3-fold co-incubated with DNMT3L (0.25 ug)
• Molecular Mass: ~70 kDa
• Purity: >80% by densitometry
• Applications: Methyltransferase Assay
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μl

Gene Information

• Gene Name: DNMT3L DNA (cytosine-5-)-methyltransferase 3-like [ Homo sapiens ]
• Official Symbol: DNMT3L
• Synonyms: DNMT3L; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; cytosine 5 methyltransferase 3 like protein; human cytosine 5 methyltransferase 3 like protein; MGC1090; cytosine-5-methyltransferase 3-like protein; human cytosine-5-methyltransferase 3-like protein
• Gene ID: 29947
• mRNA Refseq: NM_013369
• Protein Refseq: NP_037501
• MIM: 606588
• UniProt ID: Q9UJW3
• Chromosome Location: 21q22.3
• Pathway: Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem
• Function: enzyme activator activity; enzyme binding; metal ion binding; protein binding