Recombinant Human TGFB1

• Cat.No.: TGFB1-196H
• Product Overview: Recombinant human TGFB1 (279-end) was expressed in E.coli cells and purified by proprietary chromatographic techniques.

Specification

• Description: TGFB1 or transforming growth factor, beta 1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. High levels of TGFB1 protein have been localized in developing cartilage, endochondral and membrane bone, and skin and play a key role in the growth and differentiation of these tissues. TGFB1 can upregulate gene expression of its own converting enzyme furin in tumor cells, and mutations in TGFB1 gene result in Camurati-Engelmann disease.
• Source: E. coli
• Species: Human
• Form: Recombinant protein stored in 1 X PBS, 10% glycerol.
• Molecular Mass: ~14 kDa
• Endotoxin: Less than 0.1 ng/μg (IEU/μg) of TNF-alpha.
• Purity: >95% by densitometry
• Applications: Cell Assay
• Storage: Stored at desiccated below -20oC. It is stable at 4oC between 2-7 days. For long term storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and mu
• Concentration: 0.2 μg/μl

Gene Information

• Gene Name: TGFB1 transforming growth factor, beta 1 [ Homo sapiens ]
• Official Symbol: TGFB1
• Synonyms: TGFB1; transforming growth factor, beta 1; DPD1, TGFB; transforming growth factor beta-1; Camurati Engelmann disease; CED; TGFbeta; TGF-beta-1; TGF-beta 1 protein; latency-associated peptide; LAP; DPD1; TGFB
• Gene ID: 7040
• mRNA Refseq: NM_000660
• Protein Refseq: NP_000651
• MIM: 190180
• UniProt ID: P01137
• Chromosome Location: 19q13.1
• Pathway: ACE Inhibitor Pathway, organism-specific biosystem; ALK1 signaling events, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem
• Function: enzyme binding; eukaryotic cell surface binding; growth factor activity; protein N-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; type II transforming growth factor beta receptor binding; type II transforming growth factor beta receptor binding