Recombinant Human HRAS(Mature form), His-tagged
Cat.No. : | HRAS-229H |
Product Overview : | Recombinant human RAS1 (2-186) was expressed in E.coli cells using an N-terminal His tag. The RAS1 mature form shows a higher activity compared to RAS1 (1-189) precursor form. |
- Specification
- Gene Information
- Related Products
Description : | The RAS gene superfamily encodes a group of closely related 21,000 dalton (p21) proteins with special affinity for guanine nucleotides (GTP). RAS and several other cellular proteins with similar biochemical properties are collectively known as G-proteins and they play key roles in a wide variety of cellular activities, including cell growth, differentiation, secretion, and protein trafficking. There are three forms of RAS gene in cells termed H-RAS, N-RAS, and K-RAS. RAS proteins play a direct causal role in human cancer and in other diseases. Mutant H-RAS, N-RAS, and K-RAS occur in varying frequencies in different tumor types. Other members of the RAS superfamily may also contribute to cancer. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Molecular Mass : | ~23 kDa |
Purity : | >95% by densitometry |
Applications : | Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog [ Homo sapiens ] |
Official Symbol : | HRAS |
Synonyms : | HRAS; v-Ha-ras Harvey rat sarcoma viral oncogene homolog; HRAS1; GTPase HRas; p21ras; H-Ras-1; p19 H-RasIDX protein; c-has/bas p21 protein; transforming protein p21; Ha-Ras1 proto-oncoprotein; c-ras-Ki-2 activated oncogene; GTP- and GDP-binding peptide B; transformation gene: oncogene HAMSV; Ras family small GTP binding protein H-Ras; CTLO; HAMSV; K-RAS; N-RAS; RASH1; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1; |
Gene ID : | 3265 |
mRNA Refseq : | NM_001130442 |
Protein Refseq : | NP_001123914 |
MIM : | 190020 |
UniProt ID : | P01112 |
Chromosome Location : | 11p15.5 |
Pathway : | ARMS-mediated activation, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Activation of RAS in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Axon guidance, organism-specific biosystem; |
Function : | GTP binding; GTPase activity; nucleotide binding; protein C-terminus binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
HRAS-2524H | Recombinant Human HRAS protein(Met1-Cys186), His-tagged | +Inquiry |
HRAS-0596H | Recombinant Human HRAS Protein (M1-R169), GST tagged | +Inquiry |
HRAS-2135H | Recombinant Human HRAS Protein | +Inquiry |
HRAS-3848H | Recombinant Human HRAS ΔC (S17N) Protein | +Inquiry |
HRAS-1097H | Recombinant Human HRAS Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HRAS-556HCL | Recombinant Human HRAS cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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