Active Recombinant Mouse Il6, Fc-tagged
| Cat.No. : | Il6-320M |
| Product Overview : | The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2. |
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- Gene Information
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| Description : | Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells. |
| Source : | HEK293 Cells |
| Species : | Mouse |
| Tag : | Fc |
| Form : | Lyophilized. Contains PBS. |
| Bio-activity : | Promotes growth of hybridoma/plasma cells at concentration |
| Molecular Mass : | 50kDa |
| Purity : | ≥95% (SDS-PAGE) |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles. |
| Concentration : | 0.1 mg /ml after reconstitution |
| Gene Name : | Il6 interleukin 6 [ Mus musculus ] |
| Official Symbol : | Il6 |
| Synonyms : | IL6; interleukin 6; interleukin-6; interleukin HP-1; B-cell hybridoma growth factor; Il-6; |
| Gene ID : | 16193 |
| mRNA Refseq : | NM_031168 |
| Protein Refseq : | NP_112445 |
| Pathway : | Adipogenesis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; |
| Function : | cytokine activity; cytokine activity; growth factor activity; interleukin-6 receptor binding; interleukin-6 receptor binding; protein binding; receptor binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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