Active Recombinant Mouse Vegfa
Cat.No. : | Vegfa-530M |
Product Overview : | Mouse VEGF 164 (164aa). |
- Specification
- Gene Information
- Related Products
Description : | Mouse vascular endothelial growth factor 164 (VEGF 164) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. It is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo and is also a chemoattractant for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It may play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. |
Source : | Sf9 Cells |
Species : | Mouse |
Tag : | N/A |
Form : | Lyophilized. |
Bio-activity : | The ED50 for stimulation of cell proliferation by human umbilical vein endothelial cells for VEGF 164 has been determined to be in the range of 1-5ng/ml. |
Molecular Mass : | ~48kDa |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For long term storage we recommend to add at least 0.1% human or bovine serum albumin. |
Gene Name : | Vegfa vascular endothelial growth factor A [ Mus musculus ] |
Official Symbol : | Vegfa |
Synonyms : | VEGFA; vascular endothelial growth factor A; vascular permeability factor; Vpf; Vegf; Vegf120; Vegf164; Vegf188; |
Gene ID : | 22339 |
mRNA Refseq : | NM_001025250 |
Protein Refseq : | NP_001020421 |
Pathway : | Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; |
Function : | cell surface binding; chemoattractant activity; cytokine activity; fibronectin binding; growth factor activity; heparin binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity; receptor agonist activity; vascular endothelial growth factor receptor 1 binding; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor binding; |
Products Types
◆ Recombinant Protein | ||
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VEGFA-534M | Recombinant Mouse VEGFA Protein | +Inquiry |
Vegfa-199V | Active Recombinant Rat Vegf165 Protein | +Inquiry |
Vegfa-145V | Active Recombinant Rat Vegf164 Protein (165 aa) | +Inquiry |
VEGFA-560H | Recombinant Human VEGFA Protein, His-tagged | +Inquiry |
◆ Lysates | ||
VEGFA-522RCL | Recombinant Rat VEGFA cell lysate | +Inquiry |
VEGFA-969CCL | Recombinant Canine VEGFA cell lysate | +Inquiry |
VEGFA-1427HCL | Recombinant Human VEGFA cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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