"Il2" Related Products

Recombinant Mouse Il2

Cat.No.: Il2-687M
Product Overview: Recombinant murine IL-2 is a 17.2 kDa protein containing 148 amino acid residues.
Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Source: E.coli
Species: Mouse
Bio-activity: Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^6 units/mg.
Molecular Mass: 17.2 kDa
AA Sequence: PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Gene Name: Il2 interleukin 2 [ Mus musculus (house mouse) ]
Official Symbol: Il2
Synonyms: Il2; Il-2; interleukin 2; interleukin-2; TCGF; T-cell growth factor
Gene ID: 16183
mRNA Refseq: NM_008366
Protein Refseq: NP_032392
UniProt ID: P04351
Chromosome Location: 3 B-C; 3 18.3 cM
Pathway: Allograft rejection; Chagas disease (American trypanosomiasis); Cytokine-cytokine receptor interaction
Function: carbohydrate binding; cytokine activity; glycosphingolipid binding

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