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Recombinant Rat Kitlg

Cat.No.: Kitlg-63R
Product Overview: Recombinant rat SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.
Description: soluble growth factor that activates c-kit tyrosine kinase receptor; important for signaling in spermatogenesis; putative regulator of Leydig cell development.
Source: E.coli
Species: Rat
Bio-activity: Determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells. The expected ED50 for this effect is 20 - 40 ng/ml.
Molecular Mass: 18.4 kDa
AA Sequence: MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Gene Name: Kitlg KIT ligand [ Rattus norvegicus (Norway rat) ]
Official Symbol: Kitlg
Synonyms: Kitlg; Mgf; SCF; Kitl; KIT ligand; kit ligand; C-kit ligand; stem cell factor KL-1; mast cell growth factor; steel factor/kit ligand; hematopoietic growth factor KL
Gene ID: 60427
mRNA Refseq: NM_021843
Protein Refseq: NP_068615
UniProt ID: P21581
Chromosome Location: 7q13
Pathway: Adaptive Immune System; Cytokine-cytokine receptor interaction; DAP12 interactions
Function: cytokine activity; growth factor activity; stem cell factor receptor binding

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