Recombinant Human TSFM

• Cat.No.: TSFM-198H
• Product Overview: TSFM, 46-346aa, Human, E.coli

Specification

• Description: TSFM is a mitochondrial translation elongation factor. It is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in TSFM are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants. Recombinant human TSFM protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.4M Urea
• Molecular Mass: 32.9 kDa(302aa)
• Protein length: 46-346aa
• AA Sequence: MSKELLMKLR RKTGYSFVNC KKALETCGGD LKQAEIWLHK EAQKEGWSKA AKLQGRKTKE GLIGLLQEGN TTVLVEVNCE TDFVSRNLKF QLLVQQVALG TMMHCQTLKD QPSAYSKVQW LTPVNLALWE AEAGGSLEGF LNSSELSGLP AGPDREGSLK DQLALAIGKL GENMILKRAA WVKVPSGFYV GSYVHGAMQS PSLHKLVLGK YGALVICETS EQKTNLEDVG RRLGQHVVGM APLSVGSLDD EPGGEAETKM LSQPYLLDPS ITLGQYVQPQ GVSVVDFVRF ECGEGEEAAE TE
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: TSFM Ts translation elongation factor, mitochondrial [ Homo sapiens ]
• Official Symbol: TSFM
• Synonyms: TSFM; Ts translation elongation factor, mitochondrial; elongation factor Ts, mitochondrial; EF TS; EF Tsmt; mitochondrial elongation factor Ts; EFTS; EFTSMT
• Gene ID: 10102
• mRNA Refseq: NM_001172695
• Protein Refseq: NP_001166166
• MIM: 604723
• UniProt ID: P43897
• Chromosome Location: 12q14.1
• Function: translation elongation factor activity