Recombinant Human TARBP2
Cat.No. : | TARBP2-209H |
Product Overview : | TARBP2, 1-345aa, Human, E.coli |
- Specification
- Gene Information
- Related Products
Description : | TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. This protein contains 3 DRBM (double-stranded RNA-binding) domains. It may also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. TARBP2 binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. Recombinant human TARBP2 protein was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea |
Molecular Mass : | 36.9 kDa (345aa) |
Protein length : | 1-345aa |
AA Sequence : | MLAANPGKTP ISLLQEYGTR IGKTPVYDLL KAEGQAHQPN FTFRVTVGDT SCTGQGPSKK AAKHKAAEVA LKHLKGGSML EPALEDSSSF SPLDSSLPED IPVFTAAAAA TPVPSVVLTR SPPMELQPPV SPQQSECNPV GALQELVVQK GWRLPEYTVT QESGPAHRKE FTMTCRVERF IEIGSGTSKK LAKRNAAAKM LLRVHTVPLD ARDGNEVEPD DDHFSIGVGS RLDGLRNRGP GCTWDSLRNS VGEKILSLRS CSLGSLGALG PACCRVLSEL SEEQAFHVSY LDIEELSLSG LCQCLVELST QPATVCHGSA TTREAARGEA ARRALQYLKI MAGSK |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Bradford assay) |
Gene Name : | TARBP2 TAR (HIV-1) RNA binding protein 2 [ Homo sapiens ] |
Official Symbol : | TARBP2 |
Synonyms : | TARBP2; TAR (HIV-1) RNA binding protein 2; Tar (HIV 1) RNA binding protein 2; RISC-loading complex subunit TARBP2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; trans-activation responsive RNA-binding protein; trans-activation-responsive RNA-binding protein; LOQS; TRBP; TRBP1; TRBP2; |
Gene ID : | 6895 |
mRNA Refseq : | NM_004178 |
Protein Refseq : | NP_004169 |
MIM : | 605053 |
UniProt ID : | Q15633 |
Chromosome Location : | 12 |
Pathway : | Gene Expression, organism-specific biosystem; MicroRNA (miRNA) Biogenesis, organism-specific biosystem; Regulatory RNA pathways, organism-specific biosystem; Small Interfering RNA (siRNA) Biogenesis, organism-specific biosystem; |
Function : | double-stranded RNA binding; protein binding; protein homodimerization activity; siRNA binding; |
Products Types
◆ Recombinant Protein | ||
TARBP2-5587R | Recombinant Rat TARBP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TARBP2-2560B | Recombinant Bovine TARBP2 Protein (1-366 aa), His-Myc-tagged | +Inquiry |
TARBP2-8483H | Recombinant Human TARBP2, His-tagged | +Inquiry |
TARBP2-10359Z | Recombinant Zebrafish TARBP2 | +Inquiry |
TARBP2-8654H | Recombinant Human TARBP2, His-tagged | +Inquiry |
◆ Lysates | ||
TARBP2-1252HCL | Recombinant Human TARBP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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