Recombinant Human MLLT11, His-tagged

• Cat.No.: MLLT11-228H
• Product Overview: MLLT11, 1-90aa, Human, His tag, E.coli

Specification

• Description: Protein AF1q, also known as MLLT11, belongs to the Mixed-Lineage Leukemia (MLL) protein family. It is located on chromosome 11q23. MLLT11 plays a role in leukemogenesis and, specifically, the progression of acute monocytic leukemia (AML). Also, expressed in embryonic brain cortex, MLLT11 is upregulated during neuronal differentiation and is thought to play a role in the development of the central nervous system. Recombinant human MLLT11 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 12.4 kDa (113aa)
• Protein length: 1-90aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMRDPVSS QYSSFLFWRM PIPELDLSEL EGLGLSDTAT YKVKDSSVGK MIGQATAADQ EKNPEGDGLL EYSTFNFWRA PIASIHSFEL DLL
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 [ Homo sapiens ]
• Official Symbol: MLLT11
• Synonyms: MLLT11; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; protein AF1q; AF1Q; ALL1 fused gene from chromosome 1q; ALL1-fused gene from chromosome 1q; RP11-316M1.10
• Gene ID: 10962
• mRNA Refseq: NM_006818
• Protein Refseq: NP_006809
• MIM: 604684
• UniProt ID: Q13015
• Chromosome Location: 1q21
• Function: molecular_function