Recombinant Human POLR2C, His-tagged
Cat.No. : | POLR2C-231H |
Product Overview : | POLR2C, 1-275aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | POLR2C is the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. Recombinant human POLR2C protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 1mM DTT, 0.1M NaCl |
Molecular Mass : | 33.8 kDa (298aa) confirmed by MALDI-TOF |
Protein length : | 1-275aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMPYANQP TVRITELTDE NVKFIIENTD LAVANSIRRV FIAEVPIIAI DWVQIDANSS VLHDEFIAHR LGLIPLISDD IVDKLQYSRD CTCEEFCPEC SVEFTLDVRC NEDQTRHVTS RDLISNSPRV IPVTSRNRDN DPNDYVEQDD ILIVKLRKGQ ELRLRAYAKK GFGKEHAKWN PTAGVAFEYD PDNALRHTVY PKPEEWPKSE YSELDEDESQ APYDPNGKPE RFYYNVESCG SLRPETIVLS ALSGLKKKLS DLQTQLSHEI QSDVLTIN |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa [ Homo sapiens ] |
Official Symbol : | POLR2C |
Synonyms : | POLR2C; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; polymerase (RNA) II (DNA directed) polypeptide C (33kD); DNA-directed RNA polymerase II subunit RPB3; RNA polymerase II subunit 3; RPB3; RPB33; RNA polymerase II subunit B3; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II 33 kDa polypeptide; RPB31; hRPB33; hsRPB3; |
Gene ID : | 5432 |
mRNA Refseq : | NM_032940 |
Protein Refseq : | NP_116558 |
MIM : | 180663 |
UniProt ID : | P19387 |
Chromosome Location : | 16q13-q21 |
Pathway : | Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; |
Function : | DNA binding; DNA-directed RNA polymerase activity; protein dimerization activity; contributes_to protein kinase activity; |
Products Types
◆ Recombinant Protein | ||
POLR2C-3332R | Recombinant Rhesus Macaque POLR2C Protein, His (Fc)-Avi-tagged | +Inquiry |
POLR2C-5579C | Recombinant Chicken POLR2C | +Inquiry |
POLR2C-3055H | Recombinant Human POLR2C, T7-tagged | +Inquiry |
POLR2C-3514R | Recombinant Rhesus monkey POLR2C Protein, His-tagged | +Inquiry |
POLR2C-7633Z | Recombinant Zebrafish POLR2C | +Inquiry |
◆ Lysates | ||
POLR2C-3036HCL | Recombinant Human POLR2C 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket