"LMX1B" Related Products

Recombinant Human LMX1B, His-tagged

Cat.No.: LMX1B-237H
Product Overview: LMX1B, 1-395aa, Human, His tag, E.coli
Description: LMX1B is a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human LMX1B protein, fused to His-tag at N-terminus, was expressed in E.coli .
Source: E.coli
Species: Human
Tag: His-tag
Form: iquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Molecular Mass: 46.5 kDa (418 aa)
Protein length: 1-395aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDIATGP ESLERCFPRG QTDCAKMLDG IKMEEHALRP GPATLGVLLG SDCPHPAVCE GCQRPISDRF LMRVNESSWH EECLQCAACQ QALTTSCYFR DRKLYCKQDY QQLFAAKCSG CMEKIAPTEF VMRALECVYH LGCFCCCVCE RQLRKGDEFV LKEGQLLCKG DYEKEKDLLS SVSPDESDSV KSEDEDGDMK PAKGQGSQSK GSGDDGKDPR RPKRPRTILT TQQRRAFKAS FEVSSKPCRK VRETLAAETG LSVRVVQVWF QNQRAKMKKL ARRHQQQQEQ QNSQRLGQEV LSSRMEGMMA SYTPLAPPQQ QIVAMEQSPY GSSDPFQQGL TPPQMPGNDS IFHDIDSDTS LTSLSDCFLG SSDVGSLQAR VGNPIDRLYS MQSSYFAS
Purity: >80 % by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 1.0 mg/ml (determined by Bradford assay)
Gene Name: LMX1B LIM homeobox transcription factor 1, beta [ Homo sapiens ]
Official Symbol: LMX1B
Synonyms: LMX1B; LIM homeobox transcription factor 1, beta; NPS1; LIM homeobox transcription factor 1-beta; LMX-1.2; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.2; MGC138325; MGC142051;
Gene ID: 4010
mRNA Refseq: NM_001174146
Protein Refseq: NP_001167617
MIM: 602575
UniProt ID: O60663
Chromosome Location: 9q33.3
Pathway: SIDS Susceptibility Pathways, organism-specific biosystem;
Function: metal ion binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.